CURRICULUM VITA
NEAL RICHARD LANGERMAN
![]()
BORN: Philadelphia, PA, 1943
EDUCATION: Atlantic City High School Atlantic City, NJ 1957-61
Franklin and Marshall College
Lancaster, PA 1961-1965, A.B. June, 1965 (Chemistry, Minors in Physics & Math)
Northwestern University
Evanston, IL 1965-69; Ph.D. August, 1969 (Physical and Biophysical Chemistry)
Yale University
New Haven, CT 1969-1970 N.I.H. Postdoctoral Fellow, December 1970
PROFESSIONAL EXPERIENCE:
Tufts University School of Medicine
Department of Biochemistry and Pharmacology
Boston, MA Assistant Professor 1970-75
Utah State University
Department of Chemistry and Biochemistry
Logan, UT Assistant Professor 1975-77
Associate Professor 1977-1983
Chemical Safety Associates, Inc. San Diego, CA President 1982-1997
Advanced Chemical Safety San Diego, CA President 1997 - present
Chemical Control Board City of Torrance, California Chairman, 1989
Editorial Board Occupational Hazards 1999 - present
Editorial Board J. Chemical Health and Safety 1999 - present
Editorial Advisory Board Laboratory Safety and Environmental
Management 1999 - present
AREAS OF SPECIALIZATION:
Environmental Regulations
OSHA Regulations
Work Place Safety Hazardous
Waste and Hazardous Chemical Management
Hazardous Material Safety
Reactive and Explosive Chemical Safety
Hazardous Material Spill Response
Compressed Gas Emergency Response
Hazardous Materials Regulations
Industrial Emergency Response
Biophysical Chemistry
Physical Chemistry of Proteins
Ultracentrifugation
Chemical Thermodynamics
CERTIFICATIONS
Registered Environmental Assessor (California), 1990 - present
Certified Environmental Inspector, 1991 - present
PROFESSIONAL MEETINGS ATTENDED:
VII International Flavin Conference, March 30, 1975, San Francisco, California
27th International Calorimetry Society, July 26-30, 1975, Seattle Washington
Scripps Institute of Oceanography (visiting Scientist and Lecturer), June, 1975,
La Jolla, California
American Society of Biological Chemists, June 1976, San Francisco, California
28th International Calorimetry Conference, September, 1976, Argonne, Illinois
International Calorimetry Conference, July 1977, Montreal, Canada
Biophysical Society, March, 1978, Washington, D.C.
International Calorimetry Conference, July 1980, Eutola, Alabama
Japanese Thermal Analysis Society, (Invited paper), November, 1981, Hamamatsu,
Japan
American Chemical Society, (Invited paper), March, 1982, Las Vegas, Nevada
American Society of Safety Engineers (local chapter), (Invited paper), April,
1984, San Diego, California
Oklahoma Safety Council, (Invited paper), August, 1984, Oklahoma City, Oklahoma
American Chemical Society, (Invited paper), April, 1985, San Diego, California
Semiconductor Safety Association Conference, May 1985, Phoenix, Arizona
American Society of Safety Engineers Conference, June, 1985, San Diego, California
Semiconductor Safety Association Conference, (Invited paper), May 1986, Phoenix,
Arizona
SEMI Conference on Gallium - Arsenide Safety, San Jose, February, 1988
American Chemical Society, Conference on Chemical Entrepreneurship, Las Vegas,
March, 1988
HAZCAT, Los Angeles, June, 1988
American Society of Safety Engineers Conference, October, 1988, San Diego, California
Semiconductor Safety Association Conference, (Invited paper), April 1990, Phoenix,
Arizona
American Society of Safety Engineers Conference, (Invited paper), April 1990,
San Diego, California
AMOCO Corporation Health & Safety Conference, (2 Invited Papers), May, 1990,
Chicago, Illinois
ACS Meeting, June 1997, San Francisco (Invited Paper)
Laboratory Safety & Environmental Management, June, 1998, Durham, NC
PUBLIC TALKS AND PAPERS READ:
Enthalpy of Oxidation of FMN, September, 1974, A.C.S. Meeting, Chicago, Illinois
Calorimetric Studies of Bacterial Bioluminescence, December, 1975, Gillette
Medical Research Center
Calorimetric Studies of Bacterial Bioluminescence, December, 1975, Brandeis
University, Massachusetts
Calorimetric Studies of Bacterial Bioluminescence, December, 1975, Naval Medical
Research Institute, Bethesda, Maryland
Calorimetric Studies of Bacterial Bioluminescence, December, 1975, N.I.H.,
Bethesda, Maryland
The Binding of Deoxy-uridylate and Fluoro-desoxyuridylate to Thymidyulate Synthetase,
September, 1976, International Calorimetry Conference, Montreal, Canada
Nucleotide Binding to Thymidylate Synthetase, July, 1977, Biophysical Society,
Washington, D.C.
Properties of Glycoluciferase Isolated from Photobacterium Leiognathi, Strain
S1, March, 1978, Biophysical Society Annual Meeting
Biology Department Seminar, March, 1978, Utah State University
Physics Department Seminar, April, 1978, Utah State University
Thermodynamic Description of Iron-Siderochrome Interaction, July, International
Calorimetry Conference
Thermodynamic Parameters of Iron Binding to Desferrisiderophores, July, 1979,
International Calorimetry Conference
Thermodynamic Studies of Flavin Binding, February, 1981, University of Georgia
Thermodynamic Studies of Flavin Binding, February, 1981, Emory University
Thermodynamic Studies of Flavin Binding, February, 1981, Duke University
Thermodynamic Studies of Flavin Binding, February, 1981, Kumanoto University
Biological Application of Reaction Calorimetry, November, 1981, Tokyo Kenki
University
Thermodynamic Studies of Flavin Binding, November, 1981, Osaka University
Thermodynamic Studies of Flavin Binding, November, 1981, Nagoya University
Thermodynamic Studies of Flavin Binding, November, 1981, Tokyo University
Biological Application of Reaction Calorimetry, November, 1981, Gifu University
Biological Application of Reaction Calorimetry, November, 1981, Nagoya University
Thermodynamic Studies of Nucleotide Binding (invited lecture at the 16th meeting
of the Japanese Society of Thermal Analysis and Calorimetry), November, 1981
My World, Below and Above, (Invited lecture to the general public as part of
the Japanese Conference), November, 1981, Hamamatsu University
Industrial Applications of Reaction Calorimetry, November, 1981, Tukibo Company
Biochemical Thermodynamics (Invited paper), March, 1982, Las Vegas, Nevada
Industry's Public Perception and Perspectives on Hazardous Waste Management,
1982, Leihigh University
The OSHA Hazard Communication Standard in the Workplace (OSHA 1910.1200), August,
1984, Oklahoma Safety Council
90 Days: The Responsibilities of the Hazardous Waste Generators, October, 1984,
National Safety Council
Hazardous Materials: Where We Are-Where We Are Headed, April, 1985, American
Society of Safety Engineers
Hazardous Material Emergencies: What We Have Learned from Disaster Review, April,
1985, American Society of Safety Engineers, San Diego, California
New Techniques and Materials: Hazardous Material Clean-up in the Semiconductor
Clean Room, May, 1985, Phoenix, Arizona
Chemical Safety: Protect Your Company from Liability, American Chemical Society,
March 1988, Las Vegas, Nevada
Chemistry of Hazardous Materials, American Society of Safety Engineers, October,
1985, San Diego, California
Hazardous Materials Management, Industrial Environmental Association of San
Diego, August, 1989
OSHA's New Emergency Response Team Standards (OSHA 1910.120), April 1990, Semiconductor
Safety Association, Phoenix, Arizona
Chemical Hazard Management, December, 1991, Eastern Analytical Symposium, Newark,
NJ
"Options for the Management of MSDSs", American Chemical Society Meeting,
Spring, 1997, San Francisco.
"Establishing a Small Spill Response Program in Laboratories", Laboratory
Safety & Environmental Management Conference, June, 1998, Durham, NC.
"Spill Response in Academic and Research Laboratories", American Chemical
Society Conference, Boston, 1998. Symposium on Small Spills.
"Using a Consultant for EH&S Projects" American Chemical Society,
New Orleans 1999 Division of Chemical Safety and Health
PUBLICATIONS:
1. F.H. Suydam, W.E. Greth and N.R. Langerman, "The Synthesis of Imidate
Hydrochlorides by Reaction of Ethyl Chloroformate with Amides and Thioamides".
J. Org. Chem., 34, 292, (1969)
2. N.R. Langerman and I.M. Klotz, "Free Energy of Subunit Interactions:
Hermerythrin". Biochemistry, 8, 4746 (1969)
3. I.M. Klotz, N.R. Langerman, and D.E. Darnall, "Quaternary Structure
of Proteins". Annual Reviews of Biochemistry, 39, 25 (1970)
4. N.R. Langerman and J.M. Sturtveant, "Calorimetric Studies of Quaternary
Structure and Ligand Binding: Hemerythrin". Biochemistry, 10, 2809
(1971)
5. I.M. Klotz, D.E. Darnall, N.R. Langerman, "Quaternary Structure of Proteins".
The Proteins (1975) 3rd Ed., 1 284-412
6. N.R. Langerman, "Physical Properties of Protein". A Table. Biology
Data Book, 2nd Ed., Vol. 1, p. 370. (Federation of American Societies for Experimental
Biology, Bethesda, Maryland, (1972)
7. S.W. Rothman, R.L. Kisliuk and N.R. Langerman, "Calorimetric Studies
of Thymidylate Synthesis". J. Biol. Chem., 248, 7845
8. N.V. Beaudette and N.R. Langerman, "Enthalpy of Oxidation and Flavin
Mononucleotide". Arch. Biochem. Biophys., 161, 125 (1974)
9. A. Ohkubo, N.R. Langerman, A.B.B Righetti and M.M. Kaplan, "Isolation
and Physical Properties of Rat Liver Alkaline Phosphatase". J. Bio. Chem.
249, 7174 (1974)
10. A. Mangold and N.R. Langerman, "Enthalpy of Oxidation of Flavin Mononucleotide
II. Temperature Dependence of In Vitro Bacterial Luciferase Bioluminescence".
Arch. Biochem. Biophys., 169, 126-133 (1975)
11. N.R. Langerman, "Calorimetric Study of the Binding of FMN to Bacterial
Luciferase" in Flavine and Flavoproteins (S.J. Singer, Ed.) 77-82
(1976)
12. N.V Beaudette and N.R. Langerman, A Review of Oxidases and Related Redox
Systems, Vol. 1 and 2". The Quarterly Review of Biology, 50, 445-446
13. N.R. Langerman, A Review of "Subunits in Biological Systems",
Amer. Sci. (1976)
14. N.R. Langerman, "Enthalpy, Entropy ,and Free Energy Values for Biochemical
Redox Reactions", Handbook of Biochemistry and Molecular Biology, p. 121
(1976)
15. P. McIlvaine and N.R. Langerman, "A Calorimetric Investigation of the
Growth of the Luminescent Bacteria Beneckea harveyi and Photobacterium
leiognathi". Biophys. J., 17, 16-25 (1977)
16. N.V. Beaudette, N.R. Langerman, R.L. Kisliuk and Y. Gaumont, "A Calorimetric
Study of the Binding of 2'-Deoxyoridine-5'-Phosphate and 5'-Fluoro-2'-Deoxyuridine-5'-Phosphate
to Thymidylate Synthetase", Arch. Biochem. Biophys. 272-278 (1977)
17. M.J. Gonzales and N.R. Langerman, "A Thermodynamic Description of the
Self-Association of Flavin Mononucleotide", Arch. Biochem. Biophys., 180
75-81 (1977)
18. C.V. Balakrishnan and N.R. Langerman, "The Isolation of a Bacterial
Glycoprotein with Luciferase Activity", Arch. Biochem. Biophys., 181,
680-682 (1977)
19. N.R. Langerman and R.L. Biltonen, "Microcalorimetry for Biological
Chemistry: Applications, Instrumentation, and Experimental Design". Methods
in Enzymology, 61, 287-311 (1978)
20. R.L. Biltonen and N.R. Langerman, "Microcalorimetry for Biological
Chemistry: Experimental Design, Data Analysis and Interpretation: Methods in
Enzymology, 61, 261-285 (1978)
21. N.R. Langerman, "The Simultaneous Determination of Heat Changes and
Light Production". Methods in Enzymology, Chapters 13 and 14, 61,
261 (1978)
22. N.V. Beaudette, and N.R. Langerman, "An Improved Method for Obtaining
Thermal Titration Curves Using Submicromolar Quantities for Proteins",
Analyt. Biochem., 90, 693-704 (1978)
23. N.V. Beaudette, N.R. Langerman, and R.L. Kisliuk, "A Calorimetric Study
of the Binding of 2'Deoxyuridine-5'-Phosphate and its Analogs to Thymidylate
Synthetase". Arch. Biochem. Biophys., 200, 410-417 (1980)
24. N.V. Beaudette and N.R. Langerman, "Thermodynamics of Nucleotide Binding
to Proteins". Critical Reviews of Biochemistry, pp. 145-170 (1980)
25. N.R. Langerman, "Biological Microcalorimetry" a review. Analytic.
Biochem., 111, 401-402
26. H. Nowak and N.R. Langerman, "Calorimetric Studies of Protein-Ligand
Reactions: Flavin Binding Proteins". Arch. Biochem. Biophys., (1982)
27. B Gould and N.R. Langerman, "A Thermodynamic Description of the Binding
of Iron to Ferrioxamine in Aqueous Solutions", Arch. Biochem. Biophys.
(1983)
28. N.R. Langerman, "Biochemical Thermodynamics", J. Chem. in Two
Year Colleges, (1982)
29. N.R. Langerman, "Thermodynamic Studies of Nucleotide Binding",
Calorimetry, Thermometry and Thermal Analysis. (1983)
30. N.R. Langerman, "Hazardous Waste Management at Academic Institution"
American Chemical Society Forum on Hazardous Waste, (1984)
31. N.R. Langerman, "Management of Hazardous Waste: Responsibilities of
Generators" National Safety Congress, (1984)
32. N.R. Langerman, "Chemical Spill Response Workshop", written and
developed for the J.T. Baker Chemical Company Office of Training Services, (1984)
33. N.R. Langerman, "Hazardous Chemical Safety" Seminar and manual
written and developed for Chemical Safety Associates, Inc. (1985)
34. N.R. Langerman, "Management of Chemical Releases" Seminar and
manual written and developed for Chemical Safety Associates, Inc. (1985).
35. N.R. Langerman, "Emergency Response in the Work Place" Seminar
and manual written and developed for Chemical Safety Associates, Inc. (1986).
36. N.R. Langerman, "Chemicals in the Work Place: Trends and Solutions"
Seminar and manual written and developed for Chemical Safety Associates, Inc.
(1986).
37. N.R. Langerman and A. Mossman "Compressed Gas Safety and Emergency
Response" Seminar and manual written and developed for Chemical Safety
Associates, Inc. (1987).
38. N. Langerman "Fire Clean-up Operations Lead to Second Emergency At
Laboratory", Occupational Health and Safety, August, 1988.
39. N. Langerman "Emergency Response Team Development and Training (in
compliance with OSHA 1910.120)", SemiConductor Safety Association Journal,
February, 1989
40. N. Langerman "Hazardous Waste Operations and Emergency Response: Summary
and Interpretation", SemiConductor Safety Association Journal, September,
1989.
41. N. Langerman "Hazardous Materials Management in the SemiConductor Industry:
Part 1", Solid State Technology, July, 1989.
42. L. Putnam and N. Langerman "OSHA Bloodborne Pathogen Exposure Control
Plan", Lewis Publishers, March, 1992.
43. N. Langerman, "Precautionary Labels for Chemical Containers",
Lewis Publishing, May, 1994.
44. N. Langerman, "Material Safety Data Sheets - Who Uses Them?" Chemical
Health & Safety, 2,#6, 1995.
45. N. Langerman, "Clean-up of Small Spills in Laboratories and Production
Areas", Chemical Health & Safety, 1999.
46. N. Langerman and H. Elston, "Regulations and Standards for the Chemical
Hygiene Officer (II): A Quick Look at Environmental Management Regulations",
Chemical Health & Safety, 6 #2, 11-14, 1999.
47. N, Langerman "Review of the Chemical Safety and Investigation Board
Report on the Sierra Chemicals, Inc. Explosion" submitted Chemical Health
& Safety, 1999.